Overview
The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer. Obtaining measurements of sodium bromide (NaBr), deuterium dilution (D2O), and D3-Creatine in a stratified sample of adults will determine the accuracy (and precision) of the available devices for ECW, TBW, and skeletal muscle mass measurements.
Eligibility
Inclusion Criteria:
- Being either male or female
- Being an adult \>20 - \<40 or \>70 years of age.
- Having a body weight of less than 440 pounds
- Being willing to comply with the study procedures
- Not having a chronic illness (e.g., diabetes, cancer, etc.)
- Must be willing to have biospecimens and imaging stored for research use
Exclusion Criteria:
- Being pregnant, attempting to become pregnant, or breastfeeding
- Having medical implants such as a pacemaker or metal joint replacements
- Having had a mastectomy, breast reduction, or breast implants
- Having hair that cannot fit in a swim cap
- Having a body weight greater than 440 pounds
- Taking medications that alter the body's fluid compartments (ex: diuretics)
- Not willing to have biospecimens and imaging stored for future research use.