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A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus

Recruiting
18-75 years
All
Phase 2

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Overview

This randomized, double-blind, placebo-controlled Phase II study is designed to evaluate the efficacy, safety, and tolerability of ASC30 oral tablets formulation in participants with Type 2 Diabetes Mellitus

Eligibility

Inclusion Criteria:

  • Have Type 2 Diabetes (T2D)
  • Have HbA1c ≥7.0% to ≤10.5% as determined by the central laboratory at screening.
  • Stable body weight (less than 5% self-reported change within the previous 3 months).
  • Have a BMI ≥23.0 kilogram/square meter (kg/m²) at screening.

Exclusion Criteria:

  • Have any prior diagnosis of type 1 diabetes mellitus (T1DM), or rare forms of diabetes mellitus
  • Have had more than 1 episode of severe hypoglycemia
  • Have poorly controlled hypertension
  • Have acute or chronic hepatitis and pancreatitis
  • Have evidence of a significant active and uncontrolled medical condition

Study details
    T2DM (Type 2 Diabetes Mellitus)

NCT07321678

Ascletis Pharma (China) Co., Limited

1 February 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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