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Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes During Cesarean Section

Virtual Reality Versus Intravenous Dexmedetomidine on Maternal Anxiety, Stress, Hemodynamics, and Neonatal Outcomes During Cesarean Section

Recruiting
18 years and older
Female
Phase N/A

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Overview

This study aims to compare the efficacy of intravenous dexmedetomidine infusion versus virtual reality (VR) in reducing maternal anxiety, stress, and hemodynamic instability during cesarean section and their effects on neonatal outcome as respiration and heart rate.

Description

Cesarean section (CS) is one of the most frequently performed surgical procedures worldwide, with steadily increasing rates across both developed and developing countries.

Dexmedetomidine, a highly selective α₂-adrenergic receptor agonist, has been increasingly utilized in obstetric anesthesia because of its anxiolytic, sedative, and analgesic properties with minimal respiratory depression.

Non-pharmacological interventions, such as virtual reality (VR), have emerged as innovative strategies for perioperative anxiety management. VR provides immersive distraction, thereby modulating pain perception and reducing stress.

Eligibility

Inclusion Criteria:

  • Age over 18 years old.
  • American Society of Anesthesiologists (ASA) physical status II.
  • Scheduled for elective cesarean section (CS) delivery under Central Neuraxial Blockade.
  • Provide informed consent and agree to participate in the study.

Exclusion Criteria:

  • Patient's refusal
  • Patient known have contraindications for Regional Anesthesia as infection at the site of injection, severe coagulopathy or allergy to local anesthetics.
  • Patient with psychiatric disorders.
  • Sensory impairment (blindness, deafness).
  • Any technical problem preventing proper fitting of the glasses to the patient face.
  • Patients with cognitive impairment, epilepsy or with claustrophobia
  • Patients with suspected eye infection
  • Signs of active labor.
  • Pregnancy related-diseases or antepartum hemorrhage.
  • Presence of Fetal distress.

Study details
    Virtual Reality
    Dexmedetomidine
    Maternal Anxiety
    Stress
    Hemodynamics
    Neonatal Outcomes
    Cesarean Section

NCT07343843

Benha University

1 February 2026

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