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Clinical Efficacy and Mechanism Exploration of MR-61 in Delaying the Progression of Myopia

Clinical Efficacy and Mechanism Exploration of MR-61 in Delaying the Progression of Myopia

Recruiting
3-18 years
All
Phase 2

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Overview

To investigate whether probiotic MR-61 can assist in slowing down the progression rate of myopia (a prospective randomized controlled study).

Description

To investigate whether probiotic MR-61 can assist in slowing down the progression rate of myopia (a prospective randomized controlled study).

Eligibility

Inclusion Criteria:

  1. Myopia is defined as spherical equivalent (SE) ≤ -0.5D.
  2. Aged between 3 and 18 years, with no restriction on gender.
  3. Cylinder power ≤ 1.50D; anisometropia of SE between both eyes ≤ 1.50D.
  4. The subject has sufficient compliance with the study follow-up; the subject or their guardian has the intention to receive treatment and has signed the informed consent form.

Exclusion Criteria:

  1. Presence of other concomitant ocular diseases;
  2. Abnormal findings on clinical slit-lamp examination;
  3. Existence of amblyopia, manifest strabismus, esotropia, or other congenital ocular diseases;
  4. Individuals with abnormal intraocular pressure or abnormal axial length of the eye;
  5. Either or both parents having a spherical equivalent (SE) ≤ -6.00D;
  6. Other conditions inconsistent with this study.

Study details
    Myopia Progressing

NCT07298824

Second Affiliated Hospital of Nanchang University

31 January 2026

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