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Detection of Brain Metastases Using a Novel Gadolinium-Weighted MRI Sequence: A Prospective Comparison

Detection of Brain Metastases Using a Novel Gadolinium-Weighted MRI Sequence: A Prospective Comparison

Recruiting
18 years and older
All
Phase N/A

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Overview

This study will evaluate a new type of MRI sequence designed to improve the visibility of brain metastases after gadolinium contrast injection. The purpose is to determine whether this novel "gadolinium-weighted" imaging method can detect more or smaller tumors than standard MRI techniques. Participants will undergo a routine brain MRI with contrast, followed by an additional scan using the new method. The goal is to improve diagnostic accuracy without increasing the contrast dose or scan time.

Eligibility

Inclusion Criteria:

  • Age 18 years or older
  • Scheduled for clinical brain MRI with gadolinium contrast
  • Known or suspected brain metastases
  • Able to provide informed consent
  • Able to lie still for the duration of the MRI examination

Exclusion Criteria:

  • Contraindications to MRI
  • Known allergy or contraindication to gadolinium-based contrast agents
  • Renal impairment (eGFR \< 30 mL/min/1.73m²)
  • Pregnant or breastfeeding
  • Inability to comply with study procedures

Study details
    Brain Neoplasms

NCT07272616

Region Stockholm

31 January 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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