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Diet and Motility in IBS

Diet and Motility in IBS

Recruiting
8-18 years
All
Phase N/A

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Overview

The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help each child with IBS feel better. The main question it aims to answer is:

  1. What types of food do the kids eat and how do these diets relate to their symptoms?
  2. Is there any motility pattern that we can identify from the kids with or without IBS using a wearable patch?
  3. What kinds of bacteria and chemicals are found in the gut and urine of children with IBS, and how are these linked to their IBS symptoms?

Participants will use the wearable patch, answer questionnaires, collect stool and urine samples, and recall their 24 hours dietary.

Eligibility

Inclusion Criteria:

Cases
  1. Males and females age 8 - 18 years
  2. Diagnosis of irritable bowel syndrome (IBS).
  3. Parental/guardian permission (informed consent) and child assent
Controls
  1. Males and Females age 8-18 years
  2. No diagnosis of abdominal pain disorder
  3. Parental/guardian permission (informed consent) and child assent

Exclusion Criteria:

Cases
  1. Allergy to adhesives
  2. Inability to cooperate with study design
  3. Antibiotic intake in the past 4 weeks
  4. Inflammatory gastrointestinal disorder diagnosis
Controls
  1. Allergy to adhesives
  2. Inability to cooperate with study design
  3. Antibiotic intake in the past 4 weeks
  4. Inflammatory gastrointestinal disorder diagnosis

Study details
    Irritable Bowel Syndrome (IBS)

NCT07283341

Children's Hospital of Philadelphia

31 January 2026

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FAQs

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