Overview
The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can show changes in the brain within the first day of a stroke due to a blocked blood vessel or bleeding in the brain. The main question it aims to answer is:
• Can FCI identify brain tissue that might recover within the first few hours after a stroke begins?
Participants will undergo a standard MRI scan and an FCI scan, as soon as possible after hospital admission.
Participants who have had a blocked blood vessel will also provide a blood sample and will have a follow up visit at 30 days for repeat of both scans and providing another blood sample.
Eligibility
Inclusion Criteria:
- Acute stroke (\<24 hours from symptom onset).
- NIHSS ≥4 and \<25 with cortical involvement and/or large vessel occlusion on baseline imaging.
- Able to undergo 3T and FCI MRI \<24h of onset.
- With or without thrombolysis.
Exclusion Criteria:
- Contraindications to MRI.
- Medically unstable.
- Unable to comprehend or comply with instructions regarding scanning
- Prior mRS of \>3.
- Identified for thrombectomy.
- Non-stroke pathology or previous cortical infarct on CT scan \> 1/3 of middle cerebral artery territory.