Overview
The goal of this clinical trial is to investigate the added value of three-dimensional transvaginal ultrasound (3D TVUS) and gel infusion sonography (3D GIS) for diagnosing a partition in the uterus (uterine septum) in comparison to magnetic resonance imaging (MRI). The main question it aims to answer is:
How well do 3D TVUS and 3D GIS detect a uterine septum compared to MRI?
Participants will receive 3D TVUS/ 3D GIS and MRI, and will complete questionnaires.
Eligibility
Inclusion Criteria:
- Women aged between 18 and 45 years
- With suspicion of a uterine septum on routine 2D TVUS
- Who are willing to give informed consent
Exclusion Criteria:
- Women aged below 18 years and over 45 years
- Prior definitive diagnosis of a uterine septum or other congenital uterine anomaly
- Prior surgery in relation to a uterine septum
- Cervical (unilateral) aplasia
- Vaginal aplasia
- Untreated obstructive vaginal septum
- Any co-morbidity that is found to interfere with the uterine measurements required in the study
- Contraindications for MRI
- Not willing or not possible to undergo transvaginal ultrasound
- Pregnancy at the time of inclusion
- Wish to conceive between inclusion and last diagnostic intervention
- Visual or pathological evidence of cervical, uterine or ovarian malignancy
- Patients with an intrauterine device (by mistake), who are not willing to remove this device before the start of the diagnostic interventions