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Home-Based Strategies for Knee Osteoarthritis

Home-Based Strategies for Knee Osteoarthritis

Recruiting
40-70 years
All
Phase N/A

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Overview

Knee osteoarthritis (KOA) is a common chronic joint condition leading to pain, functional limitations, and reduced quality of life. This randomized controlled trial aims to evaluate and compare the effectiveness of a structured home-based exercise program versus topical diclofenac sodium therapy in improving pain, functional outcomes, and health-related quality of life among adults with early-stage KOA. The results are intended to provide evidence on the optimal components of home-based conservative management strategies.

Eligibility

Inclusion Criteria:

  • Adults aged 40-70 years
  • Diagnosed with Kellgren-Lawrence grade I-II knee osteoarthritis
  • Ability to provide written informed consent

Exclusion Criteria:

  • Advanced KOA (Kellgren-Lawrence grade IV) requiring arthroplasty
  • Prior knee surgery within the past year
  • Intra-articular injections within the last 3 months
  • Neurological, rheumatological, or systemic conditions affecting mobility
  • Inability to comply with study procedures

Study details
    Knee Osteoarthritis
    Knee Osteoarthritis (Knee OA)

NCT07212647

Istanbul University - Cerrahpasa

31 January 2026

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