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Effects of Early Cardiopulmonary Rehabilitation in Patients With Acute Decompensated Heart Failure

Effects of Early Cardiopulmonary Rehabilitation in Patients With Acute Decompensated Heart Failure

Recruiting
18-80 years
All
Phase N/A

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Overview

Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction. ADHF often results in reduced physical and respiratory capacity, greater dependence on oxygen support, difficulty performing daily activities, and prolonged hospital stays. In recent years, early exercise-based cardiopulmonary rehabilitation (CPR) has been introduced as part of heart failure management. Evidence suggests that early CPR improves overall health and cardiac function in heart failure patients. However, data regarding its effects in ADHF remain limited. While some studies indicate that early CPR enhances physical function, its impact on respiratory parameters and clinical outcomes is less well established.

Cardiopulmonary rehabilitation is a multidisciplinary program designed to promote physical, psychological, and social recovery in patients with cardiovascular and pulmonary diseases. It includes exercise training, education, psychosocial support, and behavioral strategies. Early CPR specifically aims to improve cardiovascular and respiratory functions in heart failure patients. Initiating CPR in the early phase of ADHF may accelerate recovery, strengthen cardiopulmonary function, shorten hospitalization, and improve quality of life.

This study aims to evaluate the effects of early CPR on functional capacity, hemodynamic parameters, and respiratory parameters in patients with ADHF.

Eligibility

Inclusion Criteria:

  • Patients hospitalized with a diagnosis of acute decompensated heart failure
  • Being clinically stable

Exclusion Criteria:

  • Having diagnosed pulmonary, neurological, renal, liver, gastrointestinal, orthopedic or oncological pathologies
  • Having cardiomyopathy or congestive pericarditis
  • Recent heart surgery in the past 6 months
  • New or suspected thromboembolic event
  • Presence of open wounds, ulcerations or major dermatological diseases in the lower extremities

Study details
    Heart Failure

NCT07155421

Izmir Bakircay University

31 January 2026

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