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Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

Recruiting
18 years and older
All
Phase N/A

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Overview

The investigators want to test a treatment for posttraumatic stress disorder (PTSD) especially designed for military veterans and service members with mild traumatic brain injuries (TBI) and PTSD. The treatment will include individual psychotherapy sessions to manage PTSD.

Description

The objective of this study is to test a non-trauma intervention for PTSD tailored to military veterans and service members with mTBI called Non-Trauma Treatment for TBI and comorbid PTSD (T3 PTSD).

Aim1

Conduct a pilot study of the non-trauma intervention for comorbid mTBI and PTSD in a sample of n = 20 veterans and service members seeking treatment at Fort Hood, Texas.

Aim2

Establish the acceptability and feasibility of the non-trauma intervention in service members and veterans.

Eligibility

Inclusion Criteria:

  1. Ability of participant to understand and the willingness to sign a written informed consent document based on interviewer assessment and clinical judgement.
  2. Any veteran or active duty service member (age 18 or above) diagnosed with mTBI as determined by the Ohio State University Brain Injury Identification Method
  3. Participant meets diagnostic criteria for PTSD based on Clinician-Administered PTSD Scale (CAPS-5) interview with at least moderate severity (as described by the National Center for PTSD) which includes at least one Criterion B symptom, one Criterion C symptom, two Criterion D symptoms, and two Criterion E symptoms as well as meeting Criterions F and G.
  4. Participant is stable on medications at baseline assessment (i.e., no changes in medication prescriptions in the past 4 weeks).
  5. Ability to read, write, and speak English based on interviewer assessment and clinical judgement.

Exclusion Criteria:

  1. Participant is actively engaged in a behavioral intervention primarily targeting PTSD.
  2. Participant has a psychiatric problem that warrants immediate treatment as indicated in the electronic health record, flagged during testing, or confirmed by a clinician through screening or review of clinical notes.
  3. Participant demonstrates significant cognitive impairment that could impact treatment adherence/benefit based on interviewer assessment and clinical judgement.

Study details
    mTBI - Mild Traumatic Brain Injury
    PTSD
    Post Traumatic Stress Disorder

NCT07351305

The University of Texas Health Science Center at San Antonio

31 January 2026

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