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NIRS Monitoring in the NICU and AKI

NIRS Monitoring in the NICU and AKI

Recruiting
24-30 years
All
Phase N/A

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Overview

The primary objective of this study is to describe the pattern of renal tissue oxygen saturation (SrSO2) using near-infrared spectroscopy (NIRS) in premature infants <30 weeks gestational age. The secondary objective of this study is to evaluate prenatal and postnatal risk factors for acute kidney injury (AKI) in premature infants <30 weeks gestational age. The investigators will also compare various rates of complications including death, length-of-stay, and prolonged duration of mechanical ventilation, among others.

Eligibility

Inclusion Criteria:

  • Any neonate less than 30 weeks in gestational age
  • Willingness and capacity of both adult parents/guardians to sign consent

Exclusion Criteria:

  • An infant with known congenital anomalies of the kidney (i.e., grade 4 or 5 vesicoureteral reflux (VUR), posterior urethral valves, moderate or severe hydronephrosis, autosomal recessive polycystic kidney disease (ARPKD), bilateral renal agenesis or dysplasia)
  • Age >30 weeks gestational age
  • Age <24 weeks and <500 grams (will be excluded due to sensitivity of skin in this vulnerable population).
  • Clinician's decision that NIRS is not suitable due to the patient's clinical condition

Study details
    Acute Kidney Injury (AKI)
    Postnatal AKI

NCT07222722

NYU Langone Health

1 November 2025

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