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A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

A Study to Evaluate the Safety and Effectiveness of JUVÉDERM Products in Adult Participants for the Change of Their Overall Facial Appearance

Recruiting
22-65 years
All
Phase 4

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Overview

The purpose of this study is to evaluate the safety and effectiveness of JUVÉDERM products in adults seeking improvement in facial volume and/or skin quality.

Eligibility

Inclusion Criteria:

  • Must meet at least 3 of the following criteria for treatment in the face with at least 2 JUVÉDERM products, per investigator's assessment:
    • Minimal, moderate, or severe on Allergan Temple Hollowing Scale (ATHS)
    • Moderate or severe for both eyes on Allergan Infraorbital Hollow Scale (AIHS)
    • Moderate or severe on Allergan Cheek Smoothness Scale (ACSS)
    • Moderate, significant, or severe on Mid-face Volume Deficit Scale (MFVDS)
    • Moderate or severe on Nasolabial Fold Severity Scale (NLFSS)
    • Minimal, mild, or moderate on Allergan Lip Fullness Scale 2 (ALFS2)
    • Moderate or severe on Allergan Chin Retrusion Scale (ACRS)
    • Moderate or severe on Allergan Loss of Jawline Definition Scale (ALJDS)
  • Must be in good health as determined by subject's medical history, physical

    examination, and vital sign measurements.

Exclusion Criteria:

  • Prior treatment with non-permanent soft tissue fillers or fat-reducing injectables in the face or neck within 12 months prior to screening.
  • Excessively loose skin in the face and/or neck.
  • Tendency to develop hypertrophic scarring and/or keloid scarring.

Study details
    Mid Face Volume Deficit

NCT07186595

AbbVie

1 November 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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