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Feasibility Testing of the "Face-Forward-Web" Program for Chronic Orofacial Pain

Feasibility Testing of the "Face-Forward-Web" Program for Chronic Orofacial Pain

Recruiting
18-18 years
All
Phase N/A

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Overview

The goal of this study is to conduct a feasibility open pilot study (N=Up to 20) with exit interviews to assess the feasibility, acceptability, and credibility of the study protocol and Face-Forward-Web; a web-based mind-body intervention for adult patients with COP.

Deliverables: [1] Adapt and refine open pilot protocol, patient recruitment, and other study materials. [2] Assess the feasibility, acceptability, and credibility of Face-Forward-Web and optimize the intervention methodology in preparation for a future efficacy study.

This research leverages mixed methods information to evaluate the feasibility, acceptability, and credibility of Face-Forward-Web and optimize the intervention and study methodology in preparation for the subsequent pilot study and again later, for a pilot feasibility randomized control trial (RCT).

Description

Aim: Conduct a feasibility open pilot study (N=Up to 20) with exit interviews of Face-Forward-Web among adults with various chronic orofacial pain (COP). The ultimate goal of this research is to assess the feasibility, credibility, and acceptability of Face-Forward-Web and optimize the program and study methodology in preparation for a pilot feasibility randomized control trial (RCT).

Face-Forward-Web, adapted from GetActive (a mind-body program for patients with chronic musculoskeletal pain), is a mind-body program for COP and consists of 5 on-demand sessions over a web platform, each being approximately 30 minutes long. The program will teach relaxation (deep breething), mindfulness, and cognitive-behavioral skills to reduce pain and improve emotional welbeing in patients with COP. At the conclusion of each session, an interactive quiz covering the session's content is given to foster a stronger, and more long term, understanding of the material. Throughout the program, encouragements to practice and track the use of Face-Forward-Web skills are disseminated outside and/or between sessions through a variety of means (e.g, text, phone call, email), depending on individual preferenes. Home practice materials include Web-based audio and video clips (e.g., 5 min mindfulness of pain for COP) but, engagement in self-guided skill practice is also permitted.

Following program completion, there will be a one-time 15-30 minute exit interview to elicit subject perceptions of Face-Forward-Web and any recommendations to improve intervention quality. This information will be used to further adapt and optimize Face-Forward-Web prior to future efficacy testing.

Assessments: Baseline (0 weeks), post-test (5 weeks), and 3-month follow-up (17 weeks) survey assessments.

Eligibility

Inclusion Criteria:

  1. Age ≥18
  2. English fluency and literacy
  3. Nonmalignant chronic (>3 months) orofacial pain
  4. Ability and willingness to participate in the Face-Forward web-platform intervention
  5. Free of concurrent psychotropic medication 2 week prior to participation OR stable psychotropic medication dose and type for ≥ 6 weeks
  6. Pain score ≥4/10 on the Numerical Rating Scale
  7. Owns (or has easy access to) a device with internet access

Exclusion Criteria:

  1. Practice of mindfulness > 45 minutes/week in the past 3 months
  2. Participation in mind-body or cognitive-behavioral therapy in the past 3 months
  3. Severe untreated mental health disorder (e.g., psychosis)
  4. Active suicidal ideation with plan or intent
  5. Pregnancy

Study details
    Orofacial Pain
    Facial Pain

NCT06754917

Massachusetts General Hospital

31 October 2025

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