Overview
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
Eligibility
Inclusion Criteria:
- Patient at Mayo Clinic, Rochester, MN
- Age 50 years or older
- Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
- Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
- Ability to complete study questionnaires
Exclusion Criteria:
- History of previous surgery to the affected hand(s)
- Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
- Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
- Recent injury (within last 1 month) to the affected hand causing current pain
- History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
- Active use of opioid pain medication(s) or oral steroids within the last 3 months
- Fibromyalgia or central sensitization syndrome
- Hand CSI or other hand injection within the past 3 months
- History of hand LDRT within the past 3 months
- Poorly controlled diabetes (HbA1c > 10%)
- Active infection
- Current pregnancy