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Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

Recruiting
18 years and older
All
Phase 2

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Overview

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the breath before and after standard neoadjuvant therapy in people with NSCLC.

Eligibility

Inclusion Criteria:

  • Age ≥18
  • Untreated clinical stage I NSCLC amenable to upfront surgery
  • Untreated stage II to IIIB NSCLC amenable to neoadjuvant treatment followed by surgery
  • ECOG Performance Status of ≤2 Of note, the E-nose is a completely noninvasive technology (only breath samples are collected). Therefore, this intervention would have no effects on a developing human fetus. There are therefore no requirements for the study population related to contraception or pregnancy testing.

Study details
    Non-Small Cell Lung Cancer

NCT07218601

Memorial Sloan Kettering Cancer Center

1 November 2025

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