Overview
- General objective
This pilot study aims to compare the prevalence of resistance in bacteria causing UTIs among patients seeking care outside the hospital settings (CDROs) to the WHO-GLASS data.
2. Specific objectives
2-1 Primary objectives:
- Determine the resistance profiles of uropathogens and carriage strains from patients with uncomplicated UTIs attending community drug retail outlets (CDRO's) and in hospitals*.
- Compare the resistance profiles of the uropathogens from patients with uncomplicated UTIs attending CDROs and hospitals to those in the WHO-GLASS database.
- Explore the patient pathway and its impact on antibiotic use among patients presenting to CDROs and hospitals with uncomplicated UTIs.
- Determine the appropriateness of antimicrobial use in the treatment of uncomplicated UTIs among patients presenting to CDROs and hospitals
2-2 Secondary objectives:
- Compare resistance profiles among the uropathogens from patients from two neighbourhoods in Kampala.
- Examine environmental samples between the study sites to determine the presence of antibiotic residues and AMR two neighbourhoods in Kampala.
Eligibility
Inclusion criteria:
- Must have one or more of the following clinical presentations regardless of age:
acute (< 2 weeks) dysuria. increased urinary urgency and frequency, irritation, discharge. increased lower abdominal pain or discomfort and sometimes gross haematuria.
- In elderly patients with pre-existing urinary symptoms: increased acute urinary changes.
Exclusion criteria:
- People without symptoms of UTI.