Overview
The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:
- Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake?
- Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake.
Participants will:
- Visit the laboratory for a preliminary screening session to assess eligibility.
- Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber.
- Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.
Eligibility
Inclusion Criteria:
- English or French speaking
- Ability to provide informed consent
Exclusion Criteria:
- History or evidence of chronic disease
- Current use of hypolipemic medication
- Current use of hormonal contraceptives
- Current use of antidepressants
- Current use of anticoagulants
- Ongoing smoking status
- Experiencing pregnancy, puerperium, or irregular menstrual cycles