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The Role of Ceus in the Characterization of Focal Liver Lesions Indeterminate to Second-level Methods

The Role of Ceus in the Characterization of Focal Liver Lesions Indeterminate to Second-level Methods

Recruiting
18 years and older
All
Phase N/A

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Overview

The primary objective of the study is to determine the accuracy of CEUS in characterizing (as benign or malignant) focal liver lesions for which CT, MRI and/or PET have not been conclusive.

Description

The study conducted will be a non-profit, observational, non-pharmacological, cross-sectional, but also partly cohort, retrospective and prospective study. The study is cross-sectional in nature, but will require 6 months of follow-up to evaluate the gold standard reference outcome in patients diagnosed with a benign pathology that does not require further investigations, and in patients with suspected malignant lesion for which histological diagnosis has not been performed on biopsy.

Eligibility

Inclusion Criteria:

  • Age ≥18 years.
  • CEUS performed performed in the last 6 months a CT, MRI and/or PET not decisive in characterizing a liver lesion.
  • Obtaining informed consent.

Exclusion Criteria:

  • Technical impossibility to perform the ultrasound evaluation.
  • Documented allergy to the ultrasound contrast medium.

Study details
    Focal Liver Lesion

NCT06876805

IRCCS Azienda Ospedaliero-Universitaria di Bologna

16 October 2025

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