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Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Recruiting
18-89 years
All
Phase N/A

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Overview

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis.

Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease.

Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome).

Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Eligibility

Arm 1: Inclusion Criteria:

• No self-reported history of pelvic or iliac venous disease or associated symptoms

Exclusion Criteria:

  • History of pelvic or iliac venous disease or intervention
  • Contraindication to MRI examination
  • Prisoners
  • Subjects ≤ 18 years of age
  • Pregnant women
  • Adults unable to provide informed consent

Arm 2: Inclusion Criteria:

• Clinical symptoms or imaging findings compatible with left iliac vein compression syndrome

Exclusion Criteria:

  • History of pelvic or iliac venous intervention
  • Contraindication to MRI examination
  • Prisoners
  • Subjects ≤ 18 years of age
  • Pregnant women
  • Adults unable to provide informed consent

Arm 3: Inclusion Criteria:

• History of left iliac vein stent placement

Exclusion Criteria:

  • Contraindication to MRI examination
  • Prisoners
  • Subjects ≤ 18 years of age
  • Pregnant women
  • Adults unable to provide informed consent

Study details
    May-Thurner Syndrome
    Iliac Venous Compression

NCT06888024

Ningcheng Peter Li

16 October 2025

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