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A Study to Assess the Impact of Lebrikizumab on Health-Related Well-Being and Control of Skin Manifestations in Participants With Moderate-to-Severe Atopic Dermatitis

A Study to Assess the Impact of Lebrikizumab on Health-Related Well-Being and Control of Skin Manifestations in Participants With Moderate-to-Severe Atopic Dermatitis

Recruiting
18 years and older
All
Phase N/A

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Overview

The main purpose of this study is to evaluate the impact of lebrikizumab treatment on the overall well-being of adult participants with moderate-to-severe AD in real-world clinical practice settings across Europe, as measured using validated 5-item World Health Organization Well-being Index (WHO-5) and to investigate effectiveness and safety of lebrikizumab, treatment satisfaction, and long-term effect of lebrikizumab treatment on participants in terms of disease symptomatology/control, fatigue, work impairment, patient's relationship with their skin, and overall QOL among adult participants.

Eligibility

Inclusion Criteria:

  • Adult (greater than or equal to [>=] 18 years) male or female participants with diagnosis of moderate-to-severe Atopic dermatitis.
  • Adult participants prescribed lebrikizumab as part of routine/usual care to manage their moderate-to severe Atopic dermatitis.
  • Willingness and ability to participate in the study; participants must give their written consent to participate.

Exclusion Criteria:

  • Hypersensitivity to the active substances or to any of the excipients of lebrikizumab (Ebglyss®).
  • Participants with pre-existing helminth infections. These participants should be treated for helminth infection before starting lebrikizumab therapy.
  • Concomitant use of live and live attenuated vaccines.
  • Pregnant women, except when the potential benefit justifies the potential risk.
  • Participants included in a clinical trial at baseline or at any time during the planned study period.
  • Participants unable to comply with the requirements of the study or who, in the opinion of the study physician, should not participate in the study.
  • Participants for whom medical chart is inaccessible to physicians to complete baseline data collection.

Study details
    Atopic Dermatitis
    Eczema

NCT06815380

Almirall, S.A.

16 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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