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EIT Assessment of Overdistension in ARDS Patients in Prone Position

EIT Assessment of Overdistension in ARDS Patients in Prone Position

Recruiting
18 years and older
All
Phase N/A

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Overview

Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung. EIT can measure the distribution of tidal ventilation and assess overdistension and collapse during a PEEP titration in any position (prone or not).

This study aims to measure the best PEEP as a compromise between recruitment and overdistension during a PEEP trial with EIT before and just after PP.

Eligibility

Inclusion Criteria:

  • Patients hospitalized in the ICU and who suffered moderate or severe ARDS (Berlin criteria, PaO2/FiO2<150), intubated sedated, under myorelaxant and equipped with EIT
  • Over the age of 18.

Exclusion Criteria:

  • Broncho-pleural leaks
  • Pregnant or breastfeeding woman.
  • Guardianship or curatorship
  • Deprived of liberty
  • No health insurance
  • Impossibility to correctly position the EIT belt (e.g., dressings, chest drainage, etc.)
  • Contra indications to EIT (e.g., implantable cardiac defibrillator, pacemaker, instable spinal lesions)

Study details
    Acute Respiratory Distress Syndrome

NCT06536543

University Hospital, Bordeaux

21 October 2025

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