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Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Recruiting
18-70 years
Female
Phase N/A
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Overview

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

Eligibility

Inclusion Criteria:

  • Female assigned at birth
  • Pre, peri- or post-menopausal
  • Healthy weight (BMI ≥18 and ≤30 kg/m2)

Exclusion Criteria:

  • Male (assigned at birth)
  • Pregnancy, breastfeeding
  • Use of hormone replacement therapies
  • Hysterectomy
  • Body mass index >30 kg/m2
  • Diagnosed sleep apnea
  • Current smoking/Nicotine/Drug use
  • Nerve/neurologic disease
  • Cardiovascular, hepatic, renal, respiratory disease
  • Blood pressure ≥140/90 mmHg
  • Diabetes, Polycystic ovarian syndrome
  • Communication barriers
  • Prescription medications
  • Malignant cancer

Study details
    Aging
    Menopause
    Hypoxia
    Vasodilation

NCT06417177

University of Missouri-Columbia

16 October 2025

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