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Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

Recruiting
18-50 years
All
Phase N/A

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Overview

Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days

Description

The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss

Eligibility

Inclusion Criteria:

  • young, healthy volunteers who gave written informed consent

Exclusion Criteria:

  • skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Study details
    Contact Dermatitis

NCT06331390

University of Split, School of Medicine

21 October 2025

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