Overview
This study is being done to learn how 18F-FSPG PET/CT scan results may be related to the response to chemotherapy and radiation in patients with esophageal cancer.
Description
PRIMARY OBJECTIVES:
I. Evaluate the ability of 18F-FSPG PET imaging to detect tumors in patients with esophageal cancer.
Eligibility
Inclusion Criteria:
- * ≥ 18 years of age
- Patients with locally advanced esophageal cancer
- Patients with untreated documented carcinoma of the esophagus that is > 2 cm who are going to receive systemic therapy concurrently with radiation as primary therapy
- Ability to provide written informed consent in accordance with institutional policies
- Female subjects of childbearing potential must have a negative serum or urine pregnancy test within 1 week of the proposed investigational PET/CT scan(s) prior to injection of the investigational radiopharmaceutical
Exclusion Criteria:
- * Body weight ≥ 400 pounds or body habitus or disability that will not permit the
imaging protocol to be performed
- Pregnant or lactating females
- Have an allergy to intravenous contrast
- eGFR < 30