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Diffusion MRI for Quantitative Assessment of Myofascial Pain

Diffusion MRI for Quantitative Assessment of Myofascial Pain

Recruiting
18-65 years
All
Phase N/A
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Overview

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Eligibility

Inclusion Criteria:

  • Men and women 18-65 years of age
  • Ability to give informed consent
  • Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain

Exclusion Criteria:

  • Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires
  • Pregnancy or breast feeding
  • Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months
  • Mandibular fracture within last 12 months
  • Initiation of additional treatment of myofascial pain within the past 1 month
  • Received masseter Botox within the last 4 months

Study details
    Masticatory Myofascial Pain Syndrome

NCT06892041

Weill Medical College of Cornell University

16 October 2025

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