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Use Misoprostol to Optimize Prevention of Cervical Cancer

Use Misoprostol to Optimize Prevention of Cervical Cancer

Recruiting
25 years and older
Female
Phase N/A
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Overview

This is a double-blind randomized controlled trial of 420 non-pregnant women undergoing cancer screening by visual inspection with acetic acid (VIA) who have Type 3 transformation zone (TZ) and randomized to receive either Misoprostol or placebo.

Eligibility

Inclusion Criteria:

  • Diagnosis of Type 3 TZ confirmed on exam prior to randomization
  • Age 25 years or older

Exclusion Criteria:

  • With Type 1 or 2 TZ prior to randomization
  • Currently pregnant
  • History of hysterectomy
  • Any cancerous lesions
  • Active cervicitis

Study details
    Cervical Cancers

NCT06669533

University of Alabama at Birmingham

16 October 2025

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