Image

Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty in Esophageal Atresia vs. Healthy Peers

Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty in Esophageal Atresia vs. Healthy Peers

Recruiting
6-18 years
All
Phase N/A

Powered by AI

Overview

Esophageal atresia is the most common congenital anomaly of the esophagus and is caused by abnormal development of the esophagus during intrauterine life. In children with esophageal atresia, structural abnormalities due to congenital anomalies and tracheoesophageal fistula, tracheomalacia, respiratory problems, recurrent respiratory tract infections, structural abnormalities, surgical interventions for repair and treatment, and decreased physical activity levels may negatively affect pulmonary function, effective coughing, muscle strength, exercise capacity, posture, motor function, and quality of life. This study aims to compare physical characteristics, body composition, pulmonary function and muscle strength, peak cough flow, posture assessment, peripheral muscle strength test, motor function, exercise capacity, physical activity level, fatigue, frailty and quality of life between children with esophageal atresia and their healthy peers.

Eligibility

Esophageal atresia group

Inclusion Criteria:

  • Children with esophageal atresia who are willing to participate in the study
  • Being between the ages of 6-18,
  • Being able to cooperate with the assessments

Exclusion Criteria:

  • Being unable to cooperate with the assessments,
  • Having an orthopedic, neurological or cardiovascular problem that may affect the assessments,
  • Having a lung infection or upper respiratory tract infection in the last four weeks,
  • Being an active smoker,
  • Not being willing to participate in the study,

Control group

Inclusion Criteria:

  • Being between the ages of 6-18,
  • Being willing to cooperate with the tests to be performed,
  • Being willing to participate in the study.

Exclusion Criteria:

  • Having a musculoskeletal problem that may affect exercise performance,
  • Having any known chronic disease,
  • Having a lung infection or upper respiratory tract infection in the last four weeks,
  • Being an active smoker,
  • Not willing to participate in the study.

Study details
    Esophageal Atresia
    Healthy Children

NCT06975982

Hacettepe University

16 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.