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Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study

Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study

Recruiting
18-85 years
Female
Phase N/A

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Overview

ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a quicker recovery. In gynecologic cancer surgeries, ERAS has been shown to help patients do better, have fewer problems, and leave the hospital sooner.

A prehabilitation program, in combination with ERAS protocols, aims to optimize patients' physical and psychological condition prior to surgery for gynecological cancers. Interventions may include tailored exercise, nutritional support, respiratory training, and psychological preparation. By enhancing baseline fitness and resilience, prehabilitation improves the body's ability to tolerate surgical stress, reduces complications, and facilitates a faster, smoother recovery within the ERAS framework.

Description

The purpose of this study is to investigate the impact of multifactorial preoperative empowerment (pre-habilitation protocol) on patients with gynecological cancer who undergo oncological surgery. The objective of this study is to demonstrate whether the implementation of pre-habilitation program empowerment as opposed to its non-implementation leads to an improvement in quality of life, a reduction in days of hospitalization, a reduction in immediate (up to discharge) and long term (up to 40th post-surgery day) postoperative complications (as measured with the Clavien Dindo system), a reduction in hospital readmission rates, and postoperative morbidity and mortality.

Eligibility

Inclusion Criteria:

  • Type of gynecological malignancy: endometrial cancer, ovarian cancer, cervical cancer, treated with laparotomy after the decision of the gynecological-oncology unit (positive opinion of the Multidisciplinary Tumor Board - MDT)
  • Patient age: 18 to 85 years
  • General condition of the patient: ASA score I-III
  • Consent to implement the accelerated recovery protocol - Enhanced recovery after surgery (ERAS)
  • Sufficient understanding of the Greek language
  • Provision of signed, after thorough information, consent to participate in the study

Exclusion Criteria:

  • Women with performance status: ECOG >2 and ASA score >III
  • Women who have not been informed and have given written consent

Study details
    ERAS
    Compliance
    Quality of Life (QOL)
    Excercise
    Immunonutrition
    Post Operative Pain
    Laparotomy Patients
    Surgical Complication
    Gynaecological Malignancies
    Gynaecologic Cancer
    Gynaecological Oncology

NCT07210164

Aristotle University Of Thessaloniki

16 October 2025

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