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Evaluation of CT-XPI

Evaluation of CT-XPI

Recruiting
18 years and older
All
Phase 2

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Overview

The goal of this clinical trial is to learn if a new computed tomography (CT) lung perfusion imaging method is as effective as standard of care (SOC) CT imaging. The main question it aims to answer is:

  • Does the new contrast-free method provide more information about lung perfusion than SOC?

Participants will undergo a 30 minute chest CT.

Description

The purpose of the study is to evaluate X-ray Pulsatility Index using prospectively acquired dynamic CT, which is different from conventional static CT scans.

The primary objective of this study is to collect dynamic CT scan data with human participants using high frame rate imaging methods to produce a map of lung perfusion.

Eligibility

Inclusion Criteria:

  • Age 18 years or older
  • Able to sign and date the informed consent form
  • Will undergo a clinically-indicated CT exam of the head, neck, chest, abdomen, pelvis, or extremities

Exclusion Criteria:

  • Pregnant or lactating
  • In need of urgent or emergent care
  • Have any conditions that, in the opinion of the PI or designee, would interfere with the evaluation of the results or constitute a health hazard for the participant

Study details
    CT Scan
    Computed Tomography

NCT07192133

University of Wisconsin, Madison

16 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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