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Urine Methylation Markers in UTUC

Urine Methylation Markers in UTUC

Recruiting
18 years and older
All
Phase N/A
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Overview

This is a research study to measure DNA markers in the urine of patients with upper tract urothelial cancer (UTUC) before surgery and during follow-up visits. Identifying these DNA markers could improve diagnosis before surgery, help assess risk, and predict early recurrence of the cancer. Urine samples will be de-identified and sent to Zymo/Pangea Research Corporation for analysis. The results of this test will be compared to the traditional tests in upper tract urothelial cancer, such as cells in the urine and tissue biopsy.

Eligibility

Inclusion Criteria:

  • >=18 years
  • Primary UTUC

Exclusion Criteria:

  • Patients who do not understand and/or are unwilling to sign a written informed consent

Study details
    Upper Tract Urothelial Cancer

NCT06805630

Duke University

16 October 2025

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