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Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

Recruiting
18 years and older
All
Phase N/A

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Overview

This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.

Description

Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.

Eligibility

Inclusion Criteria:

  • Participants diagnosed with Dupuytren's Contracture.
  • Willing to undergo ultrasound-guided needle knife dissection

Exclusion Criteria:

  • Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
  • Active hand infections, open wounds, or dermatological conditions in the treatment area.
  • Coagulopathy or use of anticoagulant that cannot be safely paused
  • Neuromuscular disorders affecting hand function
  • Pregnancy or breastfeeding
  • Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
  • Known hypersensitivity to local anesthetics.

Study details
    Dupuytren Contracture

NCT06788847

Mohamed Maher Ismail Ahmed Elashmawy

16 October 2025

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