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Cognitive Recovery After Post Stroke Delirium (RECOVER)

Cognitive Recovery After Post Stroke Delirium (RECOVER)

Recruiting
60 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

RECOVER is a Proof-of-Concept study on cognitive functioning following a longitudinal design with three measurements (during the acute- and post-acute phases of a stroke and a 3-month follow-up) and two equally-sized stroke patient groups: a post-stroke delirium(PSD), and a non-PSD group (control group). Cognitive functioning will be assessed using a multi-component neuropsychological assessment and tasked-based functional MRI (introducing a modified working memory task).

Eligibility

Inclusion Criteria:

  • Age ≥ 60 years
  • Ischemic stroke: Stroke Onset ≤ 96h, hospital admission ≤ 48h
  • NIHSS ≥ 1
  • Informed consent by patient or legal guardian

Exclusion Criteria:

  • Aphasia
  • Pre-existing conditions such as Dementia, psychiatric disorders (e.g., Depression, Schizophrenia)
  • MRI contraindication such as certain metal implants
  • Reduced consciousness, defined as Glasgow Coma Scale (GCS) ≤ 8
  • Delirium onset before study enrollment

Study details
    Post Stroke Delirium
    Cognitive Functioning After Stroke

NCT06680336

University Hospital Tuebingen

16 October 2025

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