Overview

Explore the effect of remifentanil on pruritus and paresthesia induced by fospropofol disodium in adults

Eligibility

Inclusion Criteria:

• Age 18-80 years old, plans to undergo elective non-cardiac surgery under general anesthesia.
• ASA I-II;
• The operation duration > 30 min;
• BMI 18-30kg /m2；
• Sign the informed consent form.

Exclusion Criteria:

• history of drug abuse or alcohol dependence;
• used sedative or analgesic drugs before operation;
• with severe liver and kidney function impairment;
• allergic to propofol and lipids;
• surgery that directly affect hemodynamics with surgical operations, such as macrovascular surgery;
• abnormal coagulation function, endocrine diseases or other effects on hemodynamic status;
• Participation in other clinical researchers in the past 3 months