Overview
This is an observational study aiming to investigate the association between elevated plasma D-dimer levels and the inflammatory response, as well as the impact on survival in adult patients with community acquired pneumonia.
the study participants will be subjected to sampling for D dimer and calculation of CURB 65 score. this aims to find the relation between them
Description
Community-acquired pneumonia (CAP) is a common and potentially life-threatening infection that affects millions of individuals worldwide each year.
D-dimer is a fibrin degradation product that is elevated in many conditions associated with inflammation and coagulation activation, including pneumonia.
This is an observational study including a minimum of 50 patients with CAP
Patients who will be admitted at Chest department, or coming to the outpatient clinic Ain-Shams University Hospitals with CAP and have the following inclusions:
- age ≥18 years
- diagnosis of CAP based on clinical symptoms, laboratory findings, and radiological evidence.
- Did not have any clinical or radiological signs suggesting Covid pneumonia Exclusion criteria Patients with a history of coagulation disorders, cancer, or other chronic diseases, or refusal to participate.
All patients will be subjected to the following: -
- Full medical history, demographics
- Thorough clinical examination.
- laboratory values (including white blood cell count, CRP, and D-dimer), With pre and post sample known precautions (8).
- Radiological findings (CXR).
- Severity of illness (based on the CURB-65 score).
Eligibility
Inclusion Criteria:
- Patients who will be admitted at Chest department, or coming to the outpatient
clinic Ain-Shams University Hospitals with CAP and have the following inculsions:
- age ≥18 years
- diagnosis of CAP based on clinical symptoms, laboratory findings, and radiological evidence.
Exclusion Criteria:
- Patients with a history of coagulation disorders, cancer, or other chronic diseases, or refusal to participate.
- patients who have any clinical or radiological signs suggesting Covid pneumonia.