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Effect of Eccentric Exercise on Spasticity, Walking and Balance in Spastic Cerebral Palsy

Effect of Eccentric Exercise on Spasticity, Walking and Balance in Spastic Cerebral Palsy

Recruiting
6-18 years
All
Phase N/A

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Overview

Our clinical research study is planned as a randomized controlled study and will use a stratified randomization method. The aim of this study is to investigate the effects of eccentric exercise training on spasticity, walking and balance in individuals with spastic Cerebral Palsy (CP). Individuals with spastic unilateral SP (hemiparetic) and bilateral SP (diparetic) diagnosis, Gross Motor Function Classification System (GMFCS) Level I, II and III, aged between 6-18 years will be included in the study.

Description

As a result of the G-power analysis, it was revealed that a total of 42 individuals should be included in the control and study groups. In our study, a control group of 21 people (Neurodevelopmental Treatment Group-NGT/2 days per week, 40 minutes) and an experimental group (Neurodevelopmental Treatment + Eccentric Exercise Group-NGT+EE/2 sessions per week, 20 minutes NGT + 30 minutes eccentric exercise program) will be formed. After the initial evaluations, 2 physiotherapy sessions per week will be applied to both groups for 8 weeks and then the final evaluations will be made and the obtained data will be compared with the initial evaluation data to reveal the statistical effect of eccentric exercises on spasticity, walking and balance parameters.

The hypotheses of the study are as follows:

H1: Eccentric exercise training for spastic lower extremity muscles in individuals with spastic cerebral palsy has an effect on spasticity severity.

H2: Eccentric exercise training for spastic lower extremity muscles in individuals with spastic cerebral palsy has an effect on gait parameters.

H3: Eccentric exercise training for spastic lower extremity muscles in individuals with spastic cerebral palsy has an effect on balance parameters.

H4: Eccentric exercise training for spastic lower extremity muscles in individuals with spastic cerebral palsy has an effect on quality of life, activities of daily living (ADL), and participation.

Eligibility

Inclusion Criteria:

  • Being between the ages of 6-18 and diagnosed with spastic hemiparetic or spastic diparetic CP,
  • Being at level I, II or III according to GMFCS,
  • Having increased muscle tone in hip flexor, hip adductor, knee flexor, knee extensor or ankle plantar flexor muscles according to MTS,
  • Giving informed consent including detailed information prepared for the study (by parent/guardian).

Exclusion Criteria:

  • Having received botox or surgery in the last 6 months.
  • Not signing the consent form.
  • Having limited cooperation regarding perception or performance of exercises required for the study.
  • Having a systemic disease in addition to CP.

Study details
    Cerebral Palsy
    Spastic

NCT06676540

Lokman Hekim University

21 October 2025

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