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Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

Recruiting
21 years and older
All
Phase N/A

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Overview

The purpose of this study is to evaluate the safety and performance of the ELS to treat urinary stones. The ELS is intended to break urinary stones into small fragments that can pass during or after the procedure with less or no discomfort. Eligible patients are male or females, age 21 or older, with a single urinary stone in the ureter. Participants will undergo the ELS procedure and then be evaluated 30 days later for the presence or absence of urinary stone fragments on a CT scan. Other outcome measures will be changes in pain, quality of life, and return to normal daily activities/work.

Eligibility

Inclusion Criteria:

  • Male or Female aged >=21 Years
  • Provides written informed consent
  • One urinary stone within the ureter, size >=5 mm and <=10 mm
  • Stone is indicated for Shock Wavve Lithotrips Per AUA 2016 guidelines
  • Urinary stone is present on a CT scan within past 14 days

Exclusion Criteria:

  • Anatomic presentations that would preclude obtaining an acoustic window for the ultrasound treatment
  • Medical Expulsion Therapy (e.g., Flomax)
  • Non-calcium based stones (e.g., uric acid stones)
  • Untreated UTI
  • Presence of abnormal skin conditions in the area to be treated
  • Coagulation abnormality
  • Inability to lay still for 30 minutes
  • Pregnant
  • Abnormal Kidney Function
  • Any genitourinary history or procedure that has altered anatomy (e.g. urinary tract reconstruction)

Study details
    Kidney Calculi; Ureteral Calculi

NCT06942949

Avvio Medical

21 October 2025

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