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Amino Acid Supplementation in Continuous Renal Replacement Therapy

Amino Acid Supplementation in Continuous Renal Replacement Therapy

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

ICU patients treated with continuous renal replacement therapy is recruited prior to start of treatment.

Blood samples are drawn and then dialysis start without amino acid supplementation. After a few hours samples are drawn from blood and dialysate. Then patients are given amino acid supplementation (33.5g/24hrs) for 20-24 hours. New samples are drawn and amino acid supplementation is increased to 67g/24hrs and new samples are drawn after additional 24 hours. Then CRRT will continue with the full amino acid supplementation (standars of care).

Eligibility

Inclusion Criteria:

  • Dialysis where amino acid supplementation is planned by treating physician

Exclusion Criteria:

  • Liver failure
  • Muscle disease
  • Neurodegenerative disease

Study details
    Acute Kidney Injury

NCT06835816

Karolinska University Hospital

15 October 2025

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