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Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk

Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk

Recruiting
35-64 years
All
Phase N/A

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Overview

The purpose of this research study is to investigate if a personalized intervention including parts such as navigation (focus on patient outreach efforts, missed and completed encounters), personalization (individual health benefits) and compensation (value health-related costs borne by patients) will help people reduce their chances of dying from preventable causes, including heart attacks, strokes, drinking alcohol, substance abuse, HIV, and other conditions.

Eligibility

Inclusion Criteria:

  1. Age 35 to 64
  2. Low SES (≤ $38,000 annual income, based on 2019 20th percentile NYC income, adjusted for family size)
  3. Expected mortality ≥1% per year (based on age, sex, race/ethnicity), with ≥1 of the following contributors:
    1. 10-year cardiovascular risk ≥10% (assessed by ASCVD risk tool)
    2. Heavy alcohol consumption (defined using SAMHSA binge drinking definition, drinking >4 standard drinks for men and >3 standard drinks for women on same occasion in past month)
  4. Willing to be navigated to Health and Hospitals Corporation of New York health

    system.

  5. Ability to provide written informed consent in English or Spanish

Exclusion Criteria:

  1. Receives regular care elsewhere than Health and Hospitals Corporation of New York
  2. Already diagnosed with high mortality-condition(s) that are not included in the simulation model.

Study details
    Cardiovascular Disease
    Alcohol Use Disorder
    HIV Risk
    Substance Use Disorders

NCT05828849

NYU Langone Health

15 October 2025

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FAQs

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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