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Clinical Efficacy and Safety of Robot-assisted Total Knee Arthroplasty

Clinical Efficacy and Safety of Robot-assisted Total Knee Arthroplasty

Recruiting
18-80 years
All
Phase N/A

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Overview

The purpose of this clinical trial is to understand the application value of the Orthopedic Joint Surgery Navigation System in assisting surgeons to accurately place prosthetic components in adult knee replacement surgery. It will also confirm its effectiveness and safety in clinical application.

Description

The purpose of this clinical trial is to understand the application value of the Orthopedic Joint Surgery Navigation System in assisting surgeons to accurately place prosthetic components in adult knee replacement surgery. It will also confirm its effectiveness and safety in clinical application. The main questions it aims to answer are:

Does the Orthopedic Joint Surgery Navigation System improve the accuracy of prosthetic component placement in knee replacement surgery? Is the Orthopedic Joint Surgery Navigation System superior to traditional total knee replacement What medical problems do participants encounter when taking medication ABC? Researchers will compare the Orthopedic Joint Surgery Navigation System with traditional total knee replacement surgery (using a "four-in-one" osteotomy guide) to see if the Orthopedic Joint Surgery Navigation System is superior to traditional total knee replacement in terms of prosthesis three-dimensional position, force alignment, patient satisfaction, functional scores, complications, etc.

Participants will:

End-stage knee osteoarthritis patients receive total knee replacement with the Orthopedic Joint Surgery Navigation System or traditional total knee replacement surgery Visit the clinic for examination and testing every 3 months Record their imaging data, satisfaction, functional scores, complications, etc.

Eligibility

Inclusion Criteria:

  1. Subjects voluntarily participate in the trial and sign the informed consent form;
  2. Aged 18 to 80 years old (inclusive), regardless of gender;
  3. Patients who need total knee replacement surgery;
  4. Those who can communicate well with the researchers and comply with the trial requirements.

Exclusion Criteria:

  1. Patients who are allergic to the drugs used in this trial or the implant materials;
  2. Patients with immature bone development;
  3. Patients with active infection;
  4. Patients with neuropathy of the knee joint;
  5. Patients with poor bone quality that is not conducive to prosthesis fixation;
  6. Patients with general conditions or concomitant diseases that make it difficult for people to tolerate surgery;
  7. Patients with insufficient quadriceps muscle strength;
  8. Patients with insufficient skin coverage near the surgical site and intolerance to surgery;
  9. Patients with severe femoral or tibial deformities and other severe deformities outside the joint;
  10. Patients with metal implants in the joint surgical area that affect the execution of the surgical plan;
  11. Pregnant or lactating women;
  12. Patients with severe epilepsy or mental illness;
  13. Patients with alcohol dependence or drug addiction;
  14. Patients with severe coagulation disorders;
  15. Patients who have participated in or are participating in other clinical trials within one month of enrollment;
  16. Patients who are considered by the researchers to be unsuitable for participating in this clinical trial for other reasons. Those who meet any of the above exclusion criteria need to be excluded.

Study details
    Osteoarthritis
    Knee

NCT06856356

The First Affiliated Hospital of University of Science and Technology of China

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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