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An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

Recruiting
18 years and older
All
Phase 2
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Overview

A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.

Description

Evaluation of Efficacy, Safety and Tolerability of NGM120 in a Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Participants with Colorectal Cancer who have Cancer Cachexia

Eligibility

Inclusion Criteria:

  1. Documented active diagnosis of colorectal cancer.
  2. Cachexia defined by Fearon criteria of weight loss.
  3. Signed informed consent.

Exclusion Criteria:

  1. Current active reversible causes of decreased food intake.
  2. Receiving tube feedings or parenteral nutrition at the time of Screening or Randomization.
  3. Have cachexia caused by other reasons.

Study details
    Colorectal Cancer
    CRC (Colorectal Cancer)
    Cancer Cachexia

NCT07033026

NGM Biopharmaceuticals, Inc

15 October 2025

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