Image

Multimodal Biopsychosocial Teleprehabilitation for Total Knee Arthroplasty

Multimodal Biopsychosocial Teleprehabilitation for Total Knee Arthroplasty

Recruiting
18 years and older
All
Phase N/A

Powered by AI

Overview

Knee replacement surgeries are one of the most frequently performed elective surgeries, with approximately 29,000 such procedures carried out annually in Belgium. Although these surgeries have been increasingly refined over the years, leading to better surgical outcomes, there is still room for improvement in terms of pre-surgical biopsychosocial patient preparation. Such preparation aims to optimally inform patients before their surgery and to start preparing them for rehabilitation and resumption of activities after surgery. Therefore, we aim to assess the added value and feasibility of prehabilitation within the knee replacement care pathway.

The primary objective is to investigate the feasibility, acceptability and safety of multimodal biopsychosocial teleprehabilitation (BPS-teleprehab) for people undergoing total knee arthroplasty (TKA).

The secondary objective is to explore the effect of BPS-teleprehab versus best-evidence preoperative advice for people undergoing TKA on activity outcomes, functioning, pain, symptoms of central sensitization, quality of life, cognitive-emotional factors, joint awareness, satisfaction with the surgery, healthcare and medication use and productivity loss.

The tertiary objective is to explore baseline associations between the collected outcome measures, demographics and medical data in people scheduled for TKA.

Furthermore, this pilot trial will inform potential protocol modifications in preparation of an eventual fully powered randomized controlled trial to investigate the effectiveness of BPS-teleprehab in people undergoing TKA.

Eligibility

Inclusion Criteria:

  • People scheduled for elective primary TKA at one of the participating hospitals;
  • Being over 18 years old;
  • Dutch speaking/reading

Exclusion Criteria:

  • Doing activities that make them feel out of breath for 300 minutes or more per week on average;
  • Orthopedic, neurological, cardiovascular or any other condition/comorbidity that leads to an overall contraindication for moderate physical activity;
  • Cognitive impairment (≥11 on 6-item Cognitive Impairment Test and/or unable to understand the study instructions);
  • Presence of uncontrolled inflammatory arthritides (e.g., rheumatoid arthritis, gout);
  • Uncontrolled psychiatric disorders;
  • Active cancer and/or active cancer treatment ((hormonal) maintenance therapy is allowed);
  • People undergoing emergency (non-elective) TKA.

Study details
    Total Knee Arthroplasty

NCT06565377

Universitair Ziekenhuis Brussel

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.