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Long-Term Safety of Pirtobrutinib in Participants With Previously Treated Types of Blood Cancers

Long-Term Safety of Pirtobrutinib in Participants With Previously Treated Types of Blood Cancers

Recruiting
18 years and older
All
Phase 2
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The purpose of this study is to find out more about the long-term safety of pirtobrutinib in participants with previously treated types of blood cancer. Participants must have chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkins lymphoma. The study is open to those who completed the original study - J2N-MC-JZNJ (NCT04849416) and continue to benefit from treatment. Treatment will be given every 12 weeks and this study is expected to last about 5 years.

Eligibility

Inclusion Criteria:

  • Currently enrolled and active in the originator study, JZNJ. A participant is considered active in the study if they are receiving study intervention
  • Agree to comply with contraception requirements. Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies

Exclusion Criteria:

  • Are pregnant, or intend to become pregnant during the study, or within 30 days of last dose of study treatment or to breastfeed during the study or within 1 week of the last dose of study treatment

Study details
    Lymphoma
    Non-Hodgkin
    Leukemia
    Lymphocytic
    Chronic
    B-Cell
    B-cell Lymphoma

NCT07162181

Eli Lilly and Company

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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