Overview
Gastric cancer patients after total gastrectomy will be randomized to oral nutritional supplement group or control group at discharge. Patients will receive 6 months of oral nutritional supplement or normal diet after discharge. The primary and secondary outcomes will be collected.
Description
Gastric cancer patients after total gastrectomy at discharge, if she/he has nutrition risk (NRS2002≥3), then she/he will be randomized to oral nutritional supplement (ONS) group or control (C) group after discharge. In the ONS group, in addition to diet, and patients will also consume enteral nutritional powder (500ml/d，500kcal/d) lasted for 6 months. In the C group, patients will receive normal diet. Both groups will receive nutrition counseling.
The primary and secondary outcomes will be collected.
Eligibility
Inclusion Criteria:
- Informed consent of patients or their legal representatives to participate in this study
- consecutive adult (18-80 years) patients underwent radical gastrectomy (total gastrectomy)
- nutrition Risk Screening (NRS) 2002≥3 at discharge
- eastern Cooperative Oncology Group (ECOG) score of 0-2 at discharge
- normal liver and kidney function
Exclusion Criteria:
- unable to oral or consume ONS
- allergy to any ingredient in the oral nutrition powder
- pregnancy
- palliative surgery or gastric stump cancer
- congenital acquired immune deficiency disease
- severe liver and kidney diseases including active hepatitis, cirrhosis, and uremia diabetes has developed complications or uncontrolled by medications
- motor system diseases cannot complete grip strength measurement and 5-time chair stand test
- have cognitive impairment, unable to complete the relevant questionnaires
- expected to require tube feeding after discharge from the hospital