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PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT

PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT

Recruiting
18 years and older
All
Phase N/A

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Overview

In a population of ARDS patients, we explore the influence of different PEEP levels on regional ventilation distribution, ventilation homogeneity, and the center of ventilation, optimal PEEP and lung recruitment potential as well as the extent of lung collapse and overdistension as detected by 3D-EIT.

Eligibility

Inclusion Criteria:

  • patients on mechanical ventilation.
  • Diagnosis of ARDS was based on the Berlin definition
  • lung recruitment potential assessment and PEEP titration was proper for the ARDS patients determined by the attending doctor

Exclusion Criteria:

  • Under 18 years of age.
  • Pregnant women;
  • Ribcage malformation
  • Any contraindication to the use of EIT (e.g. automatic implantable cardioverter defibrillator, and implantable pumps).
  • Hemodynamic instability, unable to tolerate high PEEP;
  • High-risk individuals with pneumothorax, mediastinal emphysema, etc.

Study details
    ARDS
    Respiratory Failure

NCT06594601

Peking Union Medical College Hospital

15 October 2025

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