Overview
The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the Hispanics/Latino (H/L) diet on disease remission in H/L patients with Ulcerative Colitis (UC) and to identify biomarkers of response to dietary therapy.
Eligibility
Inclusion Criteria:
- Documented diagnosis with ulcerative colitis from medical records.
- Self-Identify as Hispanic /Latino
- Ages 16-75
- SCCAI between 3-9 (no greater than 12 bowel movements a day)
- Fecal calprotectin > 150mg/dl.
- On stable medications for their disease for the past 3 months
- Likeability of Latin foods (starchy vegetables, rice, tropical fruits, plantains)
- No recent Inflammatory Bowel Disease (IBD) related hospitalization in the last month.
Exclusion Criteria:
- Diagnosis of Crohn's Disease (CD).
- Prior ileoanal anastomosis (J-pouch) or diversion
- No recent hospitalizations on the last 4 weeks
- No Clostridium difficile or enteric infections on the last 4 weeks
- No use of probiotics on the last 4 weeks
- Patients following the specific carbohydrate diet or mediterranean diet or anti-inflammatory diet
- No active cancer or conditions limiting their ability to follow a diet (heart failure, end stage renal disease)
- Pregnancy, breastfeeding or planning to become pregnant during study period
- Use of Total Parenteral Nutrition at the time of screening and during the study period
- Other significant or life-threatening co-morbidities
- The need for antibiotic use during the study period
- Adults unable to consent
- Ages less than 16 and > 75 years old
- Prisoners