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Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness

Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness

Recruiting
18-65 years
All
Phase N/A
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Overview

The purpose of this academic lead study is to explore the effect of noninvasive neuromodulation of the CM-pf via tTIS for patients with disorders of consciousness.

Eligibility

Inclusion Criteria:

  • traumatic and nontraumatic etiology of VS/UWS or MCS according to published diagnostic criteria.

Exclusion Criteria:

  • patients in coma, with less than 1 week after acute brain insult, with fluctuating diagnosis on baseline assessment, and with a metallic cerebral implant or pacemaker, and with epilepsy.

Study details
    Disorders of Consciousness
    Severe Brain Injury
    Unresponsive Wakefulness Syndrome
    Minimally Conscious State

NCT06851156

Xijing Hospital

15 October 2025

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