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Sonographic Examination of Median Nerve Variations

Sonographic Examination of Median Nerve Variations

Recruiting
18-65 years
All
Phase N/A

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Overview

The aim of the study is to evaluate the prevalence of bifid median nerve in patients diagnosed with carpal tunnel syndrome (CTS) and whether it has a higher prevalence in CTS patients than in asymptomatic individuals, and to evaluate the characteristics of the bifid median nerve found and whether median nerve variations are predisposing factors in the development of CTS.

Description

Patients diagnosed with carpal tunnel syndrome electrophysiologically who applied to Etlik City Hospital physical therapy outpatient clinic will be included in the study.There are no sensitive groups.The research period was determined as 1 year.The sample size was done using G Power 3.1.9.4 statistical power analysis program for Windows.Based on the study conducted by Walker FO et al., the number of patients that would provide a significant difference (with a margin of error of 5% Type 1 and 20% Type 2, a study power of 80% and a confidence interval of 95%) was found to be 129 patients in total.Demographic and clinical characteristics of patients who meet the inclusion criteria and fill out the "Informed Consent Forum" will be recorded.General pain of the patients will be evaluated with the Visual Analogue Scale (Global Pain), symptom severity and functional status will be evaluated with the Boston Carpal Tunnel Questionnaire, and hand grip strength measurement will be evaluated with a dynamometer.The patient hand diagram will be marked according to the patient's sensory symptoms.Median nerve cross-sectional area will be measured at the pisiform level with ultrasound, and distal motor latency and sensory nerve conduction velocity will be measured with EMG and recorded.Median nerve stiffness will be evaluated by real-time elastography.

Eligibility

Inclusion Criteria:

  • Having typical Carpal Tunnel Sydnrome symptoms lasting longer than 3 months
  • Carpal tunnel syndrome diagnosed with EMG
  • Being a male/female >18 years of age

Exclusion Criteria:

  • History of polyneuropathy, brachial plexopathy, thoracic outlet syndrome, or surgery in the wrist area
  • Presence of inflammatory arthritis, hypothyroidism, pregnancy, rheumatological disorders, diabetes mellitus
  • Presence of peripheral vascular disease

Study details
    Carpal Tunnel Syndrome

NCT06538779

Yunus Burak Bayır

21 October 2025

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