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Neutrophil to Lymphocyte Ratio and Postdural Headache

Neutrophil to Lymphocyte Ratio and Postdural Headache

Recruiting
18 years and older
Female
Phase N/A

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Overview

This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.

Eligibility

Inclusion Criteria:

  • Women aged 18 years or older
  • Underwent elective or emergency cesarean section under spinal anesthesia
  • Had complete preoperative complete blood count (CBC) data available
  • No known hematological or inflammatory disease
  • No intraoperative complications recorded
  • Medical records accessible for postoperative follow-up regarding PDPH symptoms

Exclusion Criteria:

  • Age under 18
  • Absence of preoperative complete blood count data
  • Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy
  • Platelet count <150,000/mm³ or INR >1.5
  • Incomplete or missing medical records

Study details
    Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)
    Postdural Puncture Headache

NCT07075874

Istinye University

21 October 2025

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