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A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan

A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan

Not Recruiting
18 years and older
All
Phase 4

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Overview

The main purpose of the study is to investigate whether tirzepatide can be effectively started before Ramadan and used per label in participants with Type 2 Diabetes during the fasting month.

Eligibility

Inclusion Criteria:

  • Have a clinical diagnosis of uncontrolled Type 2 Diabetes based on the World Health Organization classification or other locally applicable diagnostic standards, and who intend to fast during Ramadan
  • Have HbA1c ≥7% within 30 days prior to screening
  • Are glucagon-like peptide-1 receptor agonist (GLP-1 RA) naïve
  • Have had stable body weight self-reported change ≤5 kilograms (kg) during the 90 days prior to screening
  • Have body mass index ≥25 kilograms per square meter (kg/m2) at screening

Exclusion Criteria:

  • Have Type 1 Diabetes or gestational diabetes
  • Have a history of chronic or acute pancreatitis
  • Have acute or chronic hepatitis
  • Have evidence of a significant, uncontrolled endocrine abnormality
  • Have a history of an active or untreated malignancy
  • Have New York Heart Association Functional Classification IV congestive heart failure
  • Have been treated with insulin within two weeks prior to screening

Study details
    Type 2 Diabetes

NCT06635057

Eli Lilly and Company

30 January 2026

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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